Sodium Chloride is a replenisher of the extracellular fluid's electrolyte by intravenous infusion. It is used for the treatment of extracellular volume depletion, dehydration and sodium depletion due to excessive diuresis, gastroenteritis or salt restriction. It may be diluted to 0.45% as a source of water in patients who are unable to take fluids by mouth. A hypertonic solution may be administered to dehydrated patients preferably in conjunction with sodium bicarbonate.